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Objective:To explore the relationship between drug evidence and core prescription for depression.Methods:We retrieved literature of TCM for depression from CNKI, VIP and Wangfang databases to November 2019, 30th as well as there cords from Ancient and Modern Medical Records Cloud Platform (V 1.5). The Excel 2010 was used to establish the standardized database of medical records. After the standardization of medicines, Ancient and Modern Medical Records Cloud Platform (V1.5) statistics methodswere used for association rules analysis, complex networks, and analysis of drugs’ frequency, medical characteristics, core prescription drugs.Results:A total of 632 effective prescriptions were included, involving a total of 527 drugs. The results of frequency of herbs showed that 23 kinds of high-frequency herbs were obtained. Bupleuri Radix was the most frequently used medicine. Most herbs are warm or flat, with pungent, sweet and bitter in taste, belonging to the lung, liver, heart and spleen meridians. A total of 25 drug-pair association and 13 TCM association were obtained by association rule analysis. Conclusions:TCM treatment for depression is mainly based on soothing the liver and regulating qi, clearing the heart and calming the nerves. Bupleuri Radix, Curcumae Radix, Paeoniae Radix Alba, Chuanxiong Rhizoma, Ziziphi Spinosae Semen are the basic prescriptions. Angelicae Sinensis Radix, Ophiopogonis Radix, Albiziae Cortex, Polygalae Radix, Poria are used as reference.
ABSTRACT
Objective To investigate the treatment effect of retrograde holmium laser lithotripsy on treatment of impacted ureteral calculi.Methods One hundred and twenty-eight patients with ureteral calculi in the Second Affiliated Hospital of Xinjiang Medical University from Feb.2011 to Dec.2013 were divided into unimpacted ureteral calculi group (70 cases) and impacted ureteral calculi (58case).The treatment efficacy,operation complications of holmium laser lithotripsy and the causes of the failure of operation were recorded.Results The stone clearance rate,operative periods and postoperative incidence of gross hematuria in the un-impaction group were 91.4％ (64/70),(36.3 ± 10.7) min and 51.4％ (36/70) respectively,significant different from those in impacted ureteral calculi(74.1％ (43/58),(45.2 ± 13.9) min and 84.5％ (49/58) respectively;x2 =6.914,t =3.736,x2 =15.535 ;P ＜ 0.05).There were no significant difference between the un-impaction group and impaction group in terms of the postoperative hospital stay periods,analgesics utilization rate,urinary tract infection rates and ureteral perforation rate.In the un-impaction group,6 cases were surgical failure due to the movement of ureteral calculi during the operation.Fifteen cases were surgical failure in the impaction group,mainly due to the stone fragments move,the ureter excessive distortion and ureteral stricture.The success rate was 58.3％ (14/24) of the stones,which were above the level of L4 in the impaction group,while the success rate was 85.3％ (29/34) of the stones that was below the level of L4 in the impaction group (x2 =5.334,P ＜ 0.05).Conclusion Impacted ureteral calculi is more difficult to deal than unimpacted stone.The operation success rate of impacted stones above the level of L4 is less than below L4 due to stone fragments and ureter distorting.